prikaz prve stranice dokumenta Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni
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master's thesis
Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni
Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2010. urn:nbn:hr:109:495276
Grabar, Vesna
Josip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
Sub-department of Applied Chemistry and instrumental Methods

Cite this document

Grabar, V. (2010). Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY. Retrieved from https://urn.nsk.hr/urn:nbn:hr:109:495276

Grabar, Vesna. "Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni." Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2010. https://urn.nsk.hr/urn:nbn:hr:109:495276

Grabar, Vesna. "Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni." Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2010. https://urn.nsk.hr/urn:nbn:hr:109:495276

Grabar, V. (2010). 'Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni', Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, accessed 25 April 2024, https://urn.nsk.hr/urn:nbn:hr:109:495276

Grabar V. Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY; 2010 [cited 2024 April 25] Available at: https://urn.nsk.hr/urn:nbn:hr:109:495276

V. Grabar, "Sinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni", Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, Osijek, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:109:495276

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TitleSinteza tiadiazina s kumarinskom jezgrom kao potrencijalnih inhibitora rasta nekih mikotoksikogenih plijesni
Title (english)Synthesis of thiadizine with the coumarine core as a potential growth inhibitor of some mycotoxigen moulds
AuthorVesna Grabar
MentorMilan Čačić (mentor)
MentorMaja Molnar (pomoć pri izradi, neposredni voditelj)
Committee memberIvica Strelec (član povjerenstva)
Committee memberMilan Čačić (član povjerenstva)
Committee memberLidija Jakobek (član povjerenstva)
Committee memberJurislav Babić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
(Sub-department of Applied Chemistry and instrumental Methods)
Osijek
Defense date and country2010-05-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Engineering
Abstract
Derivati kumarina (2H-kromen-2-ona) su heterociklički spojevi, a mnogi od njih imaju izražene biološke aktivnosti. Sadrže 2-pironsku jezgru kondenziranu sa benzenskim prstenom. Uglavnom se nalaze u biljnim vrstama. Spojevi s kumarinskom jezgrom su zbog svog inhibitornog djelovanja na rast određenih mikroorganizama našli primjenu u medicini, prehrambenoj i farmaceutskoj industriji. Posebna pozornost ovog rada je usmjerena na dizajn i sintezu novih tiadiazina iz supstituiranih kumarinskih tiosemikarbazida. Tiadiazini su također biološki aktivni spojevi s antivirusnim, antitumornim, antituberkuloznim i drugim djelovanjima. Reakcijom kondenzacije 3--bromoacetilkumarina sa odgovarajućim tiosemikarbazidima priređeni su različiti tiadiazini koji dosad nisu opisani u literaturi. Dobiveni spojevi su pročišćeni prekristalizacijom te su im određene točke tališta i elementarni sastav. Struktura pojedinih spojeva potvrđena je 1H-NMR i IR spektrometrijom te spektrometrijom masa.
Abstract (english)
The coumarine derivatives (2H-chromen-2-ones) are heterocyclic compounds, many of whom have significant biological activities. They contain 2-pyrone core that is condensed with the benzen ring. They can mostly be found in herbal species.Coumarine core based compounds are very useful in medicine, food and pharmaceutical industry, due to its specific inhibitory effects on the growth of specific microorganisms. This paper focuses special attention on the design and synthesis of he new thiadiazine from substitued coumarine thisemicarbazides. Thiadizine are also biologicly active compounds with antiviral, antitumor, antituberculosis and other effects. By reacting the condensed 3--bromoacetylcoumarine with the matching thiosemicarbazides, there were some varieties of thiadiazine created that have not been described in literature. The reaction progress was monitored with a thin layer chromotography, the attained compounds were purified by recrystallization and the specific points of melting, as well as their composition, were determined. The structure of particular compounds was confirmed with 1H-NMR i IR spectrometry, as well as with mass spectrometry.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:109:495276
Study programmeTitle: Food Technology and Process Engineering
Study programme type: university
Study level: graduate
Academic / professional title: diplomirani inženjer prehrambene tehnologije i procesnog inženjerstva (diplomirani inženjer prehrambene tehnologije i procesnog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Food Technology Osijek
Created on2016-01-18 16:45:45