Objectives: To test if there is a difference in blood pressure values, heart rate and pain intensity measured before and after the acupuncture treatment, and to determine if there is a connection between pain intensity and blood pressure values as well as heart rate. Study Design: The study is organised prospectively. Participants and Methods: 63 patients divided into four groups participated in the research. The first group was made of patients suffering from R 51 headache, the second of patients suffering from M 53.1 cervicobrachial syndrome, the third of patients suffering from M 54.4 ishciadica and the fourth group was made of patients diagnosed with both cervicobrachial syndrome and lumbar syndrome at the same time. The observed variables are: age, sex, systolic and diastolic blood pressure, heart rate and pain intensity. The measurements were taken using digital pressure gaugeand, VAS scale for pain, during ten days of acupuncture treatment. Results: The difference between the tested variables: systolic and diastolic blood pressure, heart rate and pain intensity before and after acupuncture treatment turned out to be statistically significant, showing a decrease in the values after receiving thetreatment. Having compared the default variables depending on painful entities, it has been proved that the reis no difference in values of the tested variables during acupuncture based on a certain illnesses. It showed that acupuncture affects all the default entities in a similar way. In the correlation test between blood pressure and pain intensity the reis significant connection in normotensive patients. There is no significant difference in the decrease of pain intensity based on the sex of the person. Conclusion: Blood pressure, heart rate and pain intensity decrease in a statistically significant way after applying acupuncture to all the default diagnostic enteties.