undergraduate thesis
"Bethesda"classification of cytologic findings of cervix uteri

Irena Matanić (2016)
Metadata
Title"Bethesda" klasifikacija citologije vrata maternice
AuthorIrena Matanić
Mentor(s)Branka Lončar (thesis advisor)
Abstract
CILJ ISTRAŽIVANJA: Odrediti primjerenost uzorka, razloge koji utječu na primjerenost uzoraka, učestalost negativnih i abnormalnih nalaza, učestalost pojedinih mikroorganizama, učestalost drugih ne-neoplastičnih nalaza, učestalost citoloških diferencijalnih dijagnoza. USTROJ STUDIJE: Retrospektivno istraživanje MATERIJAL I METODE: U istraživanje je uključeno 41345 ispitanica čiji su VCE razmazi bojeni i pregledani u Kliničkom zavodu za kliničku citologiju KBC Osijek tijekom 2014. godine. REZULTATI: U našoj studiji koja je obuhvatila 41345 analiziranih citoloških nalaza, primjereno je ocjenjeno 41231 (99,7%), dok je ne primjerenim ocjenjeno 114 (0,3%) nalaza. Od 114 uzoraka koji nisu zadovoljili za interpretaciju, 15 (13,2%) nije analizirano, a 99 (86,8%) je analizirano, no nije moguća procjena abnormalnosti epitela. 39894 (96,7%) uzoraka je bilo negativno na intraepitelnu leziju ili malignitet, a u 1337 (3,3%) razmaza su pronađene nađene abnormalne stanice. Abnormalne stanice su u 86,0% razmaza bile skvamoznog (pločastog) podrijetla. Fiziološka flora je nađena u 30,4% razmaza, a od patogenih mikroorganizama najbrojnija je bila "miješana vaginalna flora". ZAKLJUČAK: Klasifikacija citoloških nalaza vrata maternice uključuje diferenciranje premalignih i malignih lezija, te identifikaciju uzročnika spolno prenosivih bolesti ili njihovog citopatskog efekta.
KeywordsBethesda classification of cervical cytology Pap smear cervical intraepithelial lesions
Parallel title (English)"Bethesda"classification of cytologic findings of cervix uteri
Committee MembersBiljana Pauzar (committee chairperson)
Ljubica Glavaš-Obrovac (committee member)
Branka Lončar (committee member)
GranterSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet
PlaceOsijek
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Biochemistry
Study programme typeuniversity
Study levelundergraduate
Study programmeUniversity undergraduate study
Academic title abbreviationuniv. bacc. med. lab. diag.
Genreundergraduate thesis
Language Croatian
Defense date2016-06-08
Parallel abstract (English)
OBJECTIVES: To determine the adequacy of samples, causes that affect the adequacy of samples, frequency of the negative and abnormal findings, the incidence of certain microorganisms, the incidence of other non-neoplastic findings, the incidence of cytological differential diagnosis. STUDY DESIGN: Retrospective study. MATERIALS AND METHODS: The study included 41 345 examinees whose VCE smears were stained and examined at the Department of Clinical Cytology, Clinical Hospital Osijek, during 2014. RESULTS: In our study which included 41 345 analyzed cytological findings, 41 231 (99.7%) were rated as appropriate, while 114 (0.3%) were rated as non appropriate findings. Out of 114 samples which failed to be interpreted, 15 (13.2%) were not analyzed, and 99 (86.8%) were analyzed but it was not possible to determine the epithelial abnormality. 39 894 (96.7%) samples were negative for intraepithelial lesion or malignancy and cell abnormality was found in 1337 (3.3%) smears. Abnormal cells were of squamous (plate-like) origin in 86,0% of smears. Physiological flora was found in 30.4% of smears and the "mixed vaginal flora" was the most numerous one among pathogenic microorganisms. CONCLUSION: The classification of cytologic findings of the cervix includes the differentiation between premalignant and malignant lesions and the identification of causative agents of sexually transmitted diseases or their cytopathic effect.
Parallel keywords (Croatian)Bethesda klasifikacija citologije vrata maternice Papa razmaz cervikalne intraepitelne lezije
Resource typetext
Access conditionOpen access
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:152:139998
CommitterBisera Kopf