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master's thesis
Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. urn:nbn:hr:152:511408
Madunović, Ivana
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Madunović, I. (2019). Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju (Master's thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:511408

Madunović, Ivana. "Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:511408

Madunović, Ivana. "Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:511408

Madunović, I. (2019). 'Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 29 March 2023, https://urn.nsk.hr/urn:nbn:hr:152:511408

Madunović I. Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2019 [cited 2023 March 29] Available at: https://urn.nsk.hr/urn:nbn:hr:152:511408

I. Madunović, "Nadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:152:511408

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Metadata
TitleNadzorni obrisci u Zavodu za intenzivnu medicinu u jednogodišnjem razdoblju
Title (english)Control skin swabs in the Intensive care unit in one year period
AuthorIvana Madunović
MentorSlavica Kvolik (mentor)
Committee memberVesna Ilakovac (predsjednik povjerenstva)
Committee memberDomagoj Drenjančević (član povjerenstva)
Committee memberSlavica Kvolik (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2019-07-03, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Anesthesiology and Reanimatology
Abstract
Ciljevi istraživanja: Ispitati učestalost sterilnih i patogenih izolata nadzornih obrisaka, njihovu povezanost s budućim infekcijama te zabilježiti mjere poduzete sa ciljem sprečavanja širenja infekcije. Nacrt studije: presječno istraživanje Materijal i metode: U ovoj studiji pregledane su povijesti bolesti, terapijske liste te mikrobiološki nalazi 816 nadzornih obrisaka, od ukupno 181 pacijenta hospitaliziranih u JIL u razdoblju od 1. siječnja do 31. prosinca 2018. godine. Uspoređivani su laboratorijski nalazi na dan uzorkovanja sterilnog i patološkog nadzornog obriska. Identificirani su patogeni mikroorganizmi izolirani iz nadzornih obrisaka. Analiziran je broj pacijenata sa zabilježenom kolonizacijom nekim od patogenih mikroorganizama i njezina povezanost s kasnijim bolničkim infekcijama te mjere zabilježene sa ciljem sprječavanja širenja infekcije. Korištene statističke metode jesu: χ2 test, t-test, Fisherov egzaktni test, Mann-Whitneyev test i Pearsonov koeficijent korelacije. Rezultati: Medijan godina starosti svih ispitanika iznosi 68, s interkvartilnim rasponom 57 – 78 godina. Najčešće dijagnoze ispitivane populacije pacijenata bile su vaskularne bolesti. Udio sterilnih (normalna flora) obrisaka, učinjenih kod prethodno opisane skupine pacijenata, iznosi 67 %, dok udio patoloških obrisaka iznosi 33 %. Najčešće izolirani patogeni u nadzornim obriscima jesu: Acinetobacter baumanni (37,8 %), Enterococcus faecalis (9,4 %) i Pseudomonas aeruginosa (9,4 %). Učestalost izolacije patogenih bakterija u uzorcima obrisaka kod pacijenata koji imaju dijagnozu bolničke infekcije veća je, nego u pacijenata koji nemaju dijagnozu bolničke infekcije. Izolacija patogenih bakterija u nalazima obrisaka statistički je značajno povezana s produženim liječenjem i većim mortalitetom pacijenata (p < 0,05). „Kolonizacija“ je bila opisana kod 15 % bolesnika, a od metoda eradikacije patogenog uzročnika i sprječavanja širenja infekcije, zabilježena je dekolonizacija Octenisanom. Zaključak: Učestalost sterilnih veća je od učestalosti patoloških nadzornih obrisaka, a najčešće izolirani patogen u nadzornim obriscima jest Acinetobacter baumanni. Od metoda eradikacije patogena, zabilježena je dekolonizacija Octenisanom.
Abstract (english)
Objectives: To investigate a frequency of sterile and pathogenic isolates in control swabs, their association with future infections, and register the measures to prevent a spread of hospital infections. Study design: cross-sectional study Matherials and methods: The history of disease, therapeutic lists and microbiological findings of 181 patients hospitalized in the intensive care unit (ICU) were analyzed in this study. A total of 816 control swabs during the period from January 1st to December 31st 2018 were evaluated. Laboratory findings were compared on the day of sampling of the sterile and pathological control swabs. Pathogenic microorganisms isolated from control swabs have been identified. The number of patients with the colonization of individual pathogenic microorganisms and their association with later hospital infections was analyzed. The statistical methods used are χ2 test, t-test, Fisher's exact test, Mann-Whitney test and Pearson correlation coefficient. Results: The median age of all patients is 68 with an interquartile range of 57 – 78 years. The most common diagnosis of the examined population of patients is vascular disease. The proportion of sterile (normal flora) swabs in the previously described group of patients is 67 %, while the rate of pathological swabs is 33 %. The most commonly isolated pathogens in swabs were Acinetobacter baumanni (37,8 %), Enterococcus faecalis (9,4 %) and Pseudomonas aeruginosa (9,4 %). The frequency of isolation of pathogenic bacteria in swab samples in patients with hospital infection is greater than in patients without diagnosis of hospital infection. Isolation of pathogenic bacteria in swab findings is significantly associated with prolonged treatment and greater mortality of patients. „Colonization“ is described in 15 % of the patients, and the method of infection spread control was Octenisan decolonization. Conclusion: The frequency of sterile swabs is greater than the frequency of pathological control swabs, and the most commonly isolated pathogen was Acinetobacter baumanni. Method of eradication of the pathogen was decolonization with Octenisan.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:511408
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Medicine Osijek
Created on2019-11-05 12:41:33