undergraduate thesis
Oksidacije 1-benzotiofena (tianaftena)

Mladena Glavaš (2012)
Josip Juraj Strossmayer University of Osijek
Department of Chemistry
Metadata
TitleOksidacije 1-benzotiofena (tianaftena)
AuthorMladena Glavaš
Mentor(s)Nela Malatesti (thesis advisor)
Abstract
Aromatski heterociklički spoj 1-benzotiofen, oksidacijom se prevodi iz sulfida u odgovarajući sulfon, 1 -benzotiofen-1,1-dioksid. U ovom radu 1 -benzotiofen je oksidiran u 1-benzotiofen-1,1-dioksid korištenjem vodene otopine vodikova peroksida i ledene octene kiseline kao otapala, uz refluksiranje i to u vrlo dobrom iskorištenju od 71 %. Oksidacija 1- benzotiofena je provedena i uz oksidirajući reagens H2O2-P2O5 i acetonitril kao otapalo, sa ili bez refluksiranja. Ovisno o metodi, iskorištenja su bila 3-48%. Korištenje H2O2-P2O5 reagensa je ekološki prihvatljivo i pokazalo se kao dosta dobro oksidacijsko sredstvo, koje se može primjeniti i za druge heterocikličke spojeve koji sadrže sumpor, a u slučaju 1 - benzotiofena osobito onda kada sadrži elektron-akceptorske skupine (EWG).
Keywords1-benzothiophene 1 -benzothiophene-1 1-dioxide oxidation aqueous solution H2O2 H2O2-P2O5 reagent
GranterJosip Juraj Strossmayer University of Osijek
Department of Chemistry
PlaceOsijek
StateCroatia
Scientific field, discipline, subdisciplineNATURAL SCIENCES
Chemistry
Study programme typeuniversity
Study levelundergraduate
Study programmeChemistry
Academic title abbreviationuniv. bacc. chem.
Genreundergraduate thesis
Language Croatian
Defense date2012
Parallel abstract (English)
The aromatic heterocyclic compound 1-benzothiophene can be oxidized from its sulfide functional group into a sulfone, 1-benzothiophene-1,1-dioxide. In this work 1- benzothiophene is oxidized into 1 -benzothiophene-1,1-dioxide by heating an aqueous solution of hydrogen peroxide and glacial acetic acid as a solvent at reflux, with a very good yield of 71 %. Oxidation of 1-benzothiophene was carried out with H2O2-P2O5 reagent and acetonitrile as solvent, with and without reflux. Depending on the method, yields were ranging from 3-48%. The use of H2O2-P2O5 reagent is environmentally acceptable and it has been demonstrated to be a good oxidation agent which can be applied for other heterocyclic compound that contain sulfur, especially for 1-benzothiophenes that contain electron-withdrawing groups (EWG).
Parallel keywords (Croatian)1-benzotiofen 1 -benzotiofen-1 1-dioksid oksidacija vodena otopina H2O2 H2O2-P2O5 reagens
Resource typetext
Access conditionOpen access
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:182:705552
CommitterSanda Hasenay