undergraduate thesis
Synthesis of quaternary ammonium salts of triazole with potential cytotoxic activities

Marija Andabak (2016)
Sveučilište Josipa Jurja Strossmayera u Osijeku
Odjel za kemiju
Zavod za analitičku, organsku i primijenjenu kemiju
Metadata
TitleSinteza kvaternih amonijevih soli triazola s potencijalnim citotiksičnim djelovanjem
AuthorMarija Andabak
Mentor(s)Dean Marković (thesis advisor)
Marija Jozanović (thesis advisor)
Abstract
Kvaterni amonijevi kationi jesu poliatomski pozitivno nabijeni ioni strukture NR4+, gdje R predstavlja alkilnu ili arilnu skupinu. Zadatak ovog rada bio je provesti reakciju između alkil halogenida, odnosno u našem slučaju korišten je 1-bromooktadekan, i heterocikla 1H-1,2,4- triazola s ciljem dobivanja kvaterne amonijeve soli. Triazoli su skupina heterocikličkih spojeva molekularne formule C2H3N3 sačinjenih od peteročlanog prstena u kojem se nalaze dva atoma ugljika i tri atoma dušika. Dobivenu kvaternu amonijevu sol smo okarakterizirali 1H i 13C NMR spektrima,masenim spektrom i IR spektrom te pretpostavili njezinu moguću primjenu kao antifungalno sredstvo.
Keywordsammonium salts triazoles antifungal agents
Parallel title (English)Synthesis of quaternary ammonium salts of triazole with potential cytotoxic activities
GranterSveučilište Josipa Jurja Strossmayera u Osijeku
Odjel za kemiju
Lower level organizational unitsZavod za analitičku, organsku i primijenjenu kemiju
PlaceOsijek
StateCroatia
Scientific field, discipline, subdisciplineNATURAL SCIENCES
Chemistry
Analytic Chemistry
Study programme typeuniversity
Study levelundergraduate
Study programmeChemistry
Academic title abbreviationuniv. bacc. chem.
Genreundergraduate thesis
Language Croatian
Defense date2016-09-21
Parallel abstract (English)
Quaternary ammonium cations are polyatomic positively charged ions of the structure NR4+, where R represents alkyl or aryl group. The aim of this study was to perform a reactionbetween an alkyl halide, in our case was used 1-bromooktadekan, and heterocyclic 1H-1,2,4-triazole to get a quaternary ammonium salt. Triazoles are a group of heterocyclic compoundsof the molecular formula C2H3N3 composed of a five-membered ring containing two carbonatoms and three nitrogen atoms. The resulting quaternary ammonium salt, we characterizedwith the 1H and 13C NMR spectra, mass spectra and infrared spectra and assumed its possibleapplication as an antifungal agent.
Parallel keywords (Croatian)amonijeva sol triazoli antifungicidi
Resource typetext
Access conditionOpen access
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:182:310275
CommitterSanda Hasenay